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Department of Obstetrics, Gynecology & Reproductive Sciences
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University of Pittsburgh Physicians
300 Halket Street
Pittsburgh, PA 15213
Phone: 412-641-4220
Fax: 412-641-1133
jmr.jpg James M. Roberts , MD
Magee-Womens Research Institute
204 Craft Avenue
Pittsburgh, PA 15213
Phone: 412-641-1426
Fax: 412-641-1503
Faculty Research Interests
1959-1962: Premed: University of Michigan

1962-1966: MD: University of Michigan

1966-1967: Internal Medicine: University of Michigan

1967-1971: Residency OB/GYN: University of Michigan

1973-1975: Cardiovascular Research Institute Postdoctoral Fellow: University of California at San Francisco
Research Interests
Our group is interested in adverse pregnancy outcomes. Most of our efforts have been directed at the pregnancy complication preeclampsia. Our studies include a diverse portfolio of research approaches. Thus, we perform mechanistic studies using cells tissues and animal models; clinical research, correlative and clinical trials; behavioral studies; epidemiological and health services studies, We are studying the acute and long range consequences of these disorders to mother and baby.
(Partial listing from a total of 249 peer reviewed articles and 82 chapters and reviews)

Roberts JM, Lindheimer MD, Pearson GD, Cutler JA: Summary of the NHLBI working group on research on Hypertension During Pregnancy. Hypertension. 41 (63): 437-45, 2003.

Roberts JM, Balk JL, Bodner LM, Belizan JM, Bergel E, Martinez A: Nutrient Involvement in Preeclampsia, Journal of Nutrition, 133: 1684S-1692S, 2003.

Heine RP, Ness RB, Roberts JM; Seroprevalence of Antibodies to Chlamydia pneumoniae in Women with Preeclampsia, Amer J Obstet & Gynecol. 101: 221-26, 2003.

Agatisa PK; Ness RN; Roberts JM; Costantino JP; Kuller LH; McLaughlin MK: Impairment of endothelial function in women with a history of preeclampsia: an indicator of cardiovascular risk: Am J Physiol Heart Circ, 286, H1389-93, 2004.

Hubel CA; Bodnar LM; Many A; Harger G; Ness R B; Roberts JM: Nonglycosylated ferritin predominates in the circulation of women with preeclampsia but not intrauterine growth restriction, Clinical Chemistry. 948-51, 2004.

Patrick TE, Powers RW, Daftary AR, Ness RB, Roberts JM. Homocysteine and folic acid are inversely related in black women with preeclampsia. [Journal Article] Hypertension. 43(6): 1279-82, June 2004.

Bodnar L, Catov J, Klebanoff M, Ness R, Roberts J. Prepregnancy body mass index and the occurrence of severe hypertensive disorders of pregnancy. Epidemiology 2007; 18:234-239.

Bodnar LM, Ness RB, Harger GF, Roberts JM: Inflammation and triglycerides partially mediate the effect of prepregnancy body mass index on the risk of preeclampsia. Am J Epidemiol, 162 (12), 162 1-9, 2005

Bodnar LM, Ness RB, Markovic N, Roberts JM. The risk of preeclampsia rises with increasing prepregnancy body mass index. Annals of Epidemiology, 15: 475-82, 2005

Bodnar LM, Tang G, Ness RB, Harger G, Roberts JM. Periconceptional multivitamin use reduces the risk of preeclampsia. Am J Epidemiol 2006; 164:470-7.

Powers RW, Bodnar LM, Ness RB, Cooper KM, Gallaher MJ, Frank MP, Daftary AR, Roberts JM. Uric acid concentrations in early pregnancy among preeclamptic women with gestational hyperuricemia at delivery. American Journal of Obstetrics & Gynecology 2006;194:160.

Bodnar LM, Catov JM, Klebanoff MA, Ness RB, Roberts JM. Prepregnancy body mass index and the occurrence of severe hypertensive disorders of pregnancy. Epidemiology 2007;18:234-9.

Bodnar LM, Simhan HN, Powers RW, Frank MP, Cooperstein E, Roberts JM. High prevalence of vitamin D insufficiency in black and white pregnant women residing in the northern United States and their neonates.[see comment]. Journal of Nutrition 2007; 137:447-52.

Roberts JM, Von Versen-Hoeynck F. Maternal fetal/placental interactions and abnormal pregnancy outcomes.[comment]. Hypertension 2007; 49:15-6.

Bodnar LM, Catov JM, Roberts JM. Racial/ethnic differences in the monthly variation of preeclampsia incidence. American Journal of Obstetrics & Gynecology 2007; 196(4): 324.e1-5, April.

Bainbridge SA, Roberts JM. Uric acid as a pathogenic factor in preeclampsia. Placenta. March 2008; 29 Suppl A:S67-72

Speers PD, Powers RW, Frank MP, Hargr G, Markovic N, Roberts JM. Elevated asymmetric dimethylarginine concentrations precede clinical preeclampsia, but not pregnancies with small-for-gestational-age infants. American Journal of Obstetrics & Gynecology. Jan 2008; 198(1):112.e1-7.

Catov JM, Bodnar LM, Kip KE, Hubel C, Ness RB, Harger G, Roberts JM. Early pregnancy lipid concentrations and spontaneous preterm birth. American Journal Obstetrics & Gynecology. 2007; 197(6):610.e1-7, December
Grant Support
2 K12 HD43441-06 (Roberts, J.M.)
9/1/07 – 8/31/12 NIH/NICHD
Building Interdisciplinary Research Careers in Women’s Health.

5 P01 HD30367-13 (Hubel, C.)
7/1/08 – 6/30/13 NIH/NICHD
Mechanisms of Preeclampsia: Impact of Obesity PI Project 3: Obesity: Factors involved in the genesis of preeclampsia; CoI Administrative Core and Data Core.

1 R01 AI071386-01A1 (Haggerty, C.) (Co-I) 7/1/06 – 6/30/10 NIH/NIAID
Infection, Inflammation, and Preeclampsia

1 R01 HL091094-01 (Powers, R.) (Co-I) 7/1/08 – 6/30/13 NIH/NHLBI
Mechanisms of Preeclampsia Risk with Obesity: Role of Elevated ADMA.

5 R01 HL076532-02 (Ness, R.) (Co-I) 8/15/05 – 7/31/10 NIH/NHLBI
Fetal Growth Restriction and Maternal Cardiovascular Risk.

5 R01 HD052732-02 (Simhan, H.) (Co-I) 5/1/06 – 2/28/11 NIH/NICHD
Nutrition and the Genetics of Prematurity.

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Last Update 10/31/2014