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Department of Obstetrics, Gynecology & Reproductive Sciences
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University of Pittsburgh Physicians
300 Halket Street
Pittsburgh, PA 15213
Phone: 412-641-4220
Fax: 412-641-1133
Kelley.jpg Joseph L. Kelley, M.D.
Professor, Department of Obstetrics, Gynecology and Reproductive Sciences, Division Chief, Gynecologic Oncology Clinical Investigator, Magee Womens Research Institute Assistant Director, Gynecologic Oncology Fellowship
300 Halket Street
Pittsburgh, PA 15213
Phone: 412-641-1153
Fax: 412-641-5417
Research Interests
Dr. Kelley's research interests center around application of clinical trials for the treatment of gynecologic and breast malignancies. Dr. Kelley serves as the Co-Principal Investigator of the Gynecologic Oncology Group (GOG). Additionally, he serves as a PI on a number of studies with application of traditional as well as novel therapeutic approaches to malignancies. Dr. Kelley's area of surgical interest includes the application of sentinel node technology to gynecologic malignancies.

Dr. Kelley has strong collaborative ties with Magee-Womens Research Institute as well as the University of Pittsburgh Cancer Center and works with colleagues in area of interest such as DNA repair in breast and gynecologic malignancies as well as investigating the role of application of pharmacokenetics to these malignancies.
M.D.: St. Louis University School of Medicine, St. Louis, MO, 1985
Internship and Residency: University of Pittsburgh, Magee-Womens Hospital, Pittsburgh, PA, 1985-1989
Rutledge Fellowship: University of Texas, MD Anderson Cancer Center, Houston, TX 1988
Fellowship: University of Texas, MD Anderson Cancer Center, Houston, TX, 1989-1991
Sit A., Kelley J., Gallion HH., Kunschner A., Edwards R., Paclitaxel and Carboplatin for Recurrent or Persistent Cancer of the Cervix. Pending publication, manuscript accepted; Cancer Investigation, 2004.

2. Latimer JJ, Johnson JM, Kelly CM, Grant SG, Vogel VG, Brufsky AM, and Kelley J. (2004) Human breast cancer tumors manifest both hereditary deficiency and somatic loss of DNA (nucleotide excision) repair. Presented at the 2004 meeting of the Environmental Mutagen Society, Pittsburgh, Pennsylvania. Environmental and Molecular Mutagenesis 44:211, 2004.

3. Grant SG, Kelley JL, Vogel VG, Brufsky AM, Bigbee WL, and Latimer JJ. Variability in bone marrow mutational response in breast cancer patients treated with genotoxic chemotherapy. Presented at the joint meeting of the 9th International Conference on Environmental Mutagens and the 2005 Annual Meeting of the Environmental Mutagen Society. Environmental and Molecular Mutagenesis 577:e165.

4. Kanbour-Shakir A, Hunt, J, Carter G. Kelley J, Chivukula M. Recurrent gynandroblastoma of ovary-molecular and immunohistochemical analysis. Modern Pathology 19(3):98, 2006.

5. Carter G, Kelley J, Beriwal S, Chivukula M. Malignant mixed mullerian tumor of uterus with neuroectodermal differentiation and maturation into a ganglioneuroblastoma. Archives of Pathology & Laboratory Medicine, 130:1375, 2006.

6. Johnson JM, Miles TD, Benson AL, LaLanne NA, Mock LL, Kelley JL, Grant SG, Latimer JL. Molecular mechanism of nucleotide excision repair deficiency in novel breast cancer cell lines. Cancer Research, April 2007.

7. Richard SD, Krivak TC, Kelley JL, Zorn KK, Sukumvanich P, Ewards RP. Termination of intraperitoneal chemotherapy is driving by treatment toxicity rather than catheter dysfunction. ASCO, June 2007.

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Last Update 4/3/2010